J.Jpn. Surg. Soc.. 83(2): 231-238, 1982

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Original article

A STUDY OF THE FACTORS INFLUENCING ON THE FUNCTIONING GRAFT SURVIVAL OF CADAVERIC KIDNEY TRANSPLANTATION

Between February 1977 and April 1981, twenty-six cadaveric kidney transplantations were performed by simple surface cooling using modified Collins solution. The present investigation was undertaken in order to clarify the various factors influencing on long-term functioning survival of kidney grafts. Following results were obtained.
1) The warm ischmic time was desirable to be less than thirty minutes for obtaining good kidney function.
2) Graft survival of the six cases in which graft function was recovered within two weeks was significantly better than that of the ten cases in which graft function was recovered beyond two weeks, showing 67 and 25% of the 3-year graft survival rates, respectively.
3) Graft survival was significantly better in those incompatible for 0-2 HLA-A,B antigens than in those incompatible for 3-4 HLA-A,B antigens, the 1-and 3-year graft survival rate being 67, 67% and 29, 0%, respectively.
4) Graft survival was significantly better for the patients without preformed antibodies than for the patients with preformed antibodies, the 2-year graft survival rates being 75 and 17%, respectively.

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