[Abstract] [Full Text PDF] (in Japanese / 346KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 99(4): 241-244, 1998


Feature topic

SYSTEMATIC RESECTION FOR HEPATOCELLULAR CARCINOMA

1) Second Department of Surgery, Faculty of Medicine University of Tokyo, Tokyo, Japan
2) Department of Surgery, National Cancer Center Hospital, Tokyo, Japan

Tadatoshi Takayama1), Masatoshi Makuuchi1), Susumu Yamasaki2), Tomoo Kosuge2), Junji Yamamoto2), Kazuaki Shimada2)

We have performed systematic subsegmentectomy in patients with hepatocellular carcinoma complicated mainly by cirrhosis. Such small anatomical resections have become possible due to the introduction of intraoperative ultrasonography and of vascular occlusion techniques. As a result of our clinical experience involving 163 cases, it has been clarified that subsegmentectomy is a safe procedure (operative mortality rate, 0.6%) and results in a favorable long-term outcome (5-year survival rate, 51%). In the resected specimens, microscopic cancer spread was recognized frequently (portal venous invasion, 41% ; intrahepatic metastasis, 31%). Subsegmentectomy is therefore the first procedure of choice in patients who have small hepatocellular carcinoma and chronic hepatitis or cirrhosis.


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