J.Jpn. Surg. Soc.. 82(12): 1485-1491, 1981
Original article
EXPERIMENTAL STUDY OF ANTIPERISTALTIC GASTRIC TUBE AS A SUBSTITUTE FOR TOTALLY RESECTED SMALL INTESTINE
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Department of Surgery, Kanazawa University School of Medicine (Director: Prof. Takashi Iwa) Yukimitsu Kawaura, Yoshio Kaneko, Satoshi Ushijima, Norimasa Matsumoto, Takashi Iwa |
In group A, intestine were reconstructed whthout a substitute for the small intestine. On the contrary, in group B, intestinal continuity were restored using the antiperistaltic gastric tubes instead of the resected small intestine. The digestive function were compared in these two groups. The results were as follows:
1) Among the each ten dogs, three dogs in group A and four dogs in group B survived more than three menths.
2) Frequency of a diarrea one month after the operation was markedly low in the group B Compared with group A.
3) The serum total protein and cholesterol were similarly reduced in the both groups. However, this was more evident in group A.
4) Serum gatrin levels were similarly stable in both groups except transient hypergastrinemia one hour after the operation.
5) Regarding to the glucose tolerance test. insulin response showed normal pattern in group B.
6) On the pathological examination one month after the operation, the both groups showed a proliferation of the gastric cryps, marked mucosal fibrosis in the duodenum, and normal pancreatic islets.
From the results of our present study, it was concluded that the use of the antiperistaltic gastric tube as the substitute for the totally resected small intestine were much effective in elininating the diarrea, and in maintaning the serum protein and glucose tolerance.
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