[Abstract] [Full Text HTML] [Full Text PDF] (in Japanese / 717KB) [PDF: Members Only]

J.Jpn. Surg. Soc.. 122(2): 160-165, 2021

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Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan

Ryusei Matsuyama, Yasuhiro Yabushita, Yuki Homma, Kentaro Miyake, Gakuryu Nakayama, Yasuhiro Shimizu, Takafumi Kumamoto, Itaru Endo

Patients with perihilar cholangiocarcinoma (PHC) still have a poor prognosis after resection, and the introduction of preoperative chemotherapy is being considered to improve surgical outcomes. Therefore, identifying the cases for which preoperative chemotherapy is indicated and for which it should be introduced to improve the treatment results is a very important issue. For pancreatic cancer, which has poor resection results similar to PHC, the criteria for resection have been established since 2004, and aggressive preoperative chemotherapy is used for “borderline resectable” cases. Those criteria have contributed to improved surgical outcomes. Similar criteria are required for PHC, but a consensus has not yet been reached on unresectable/resectable limits. In the future, it will be necessary to discuss what constitutes “borderline resectable” status based on investigations of poor prognostic factors after resection experienced by many institutions.

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