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[PDF: Members Only] J.Jpn. Surg. Soc.. 122(2): 160-165, 2021
Feature topic
WHAT IS THE BORDERLINE RESECTABLE STATUS IN PERIHILAR CHOLANGIOCARCINOMA?
Patients with perihilar cholangiocarcinoma (PHC) still have a poor prognosis after resection, and the introduction of preoperative chemotherapy is being considered to improve surgical outcomes. Therefore, identifying the cases for which preoperative chemotherapy is indicated and for which it should be introduced to improve the treatment results is a very important issue. For pancreatic cancer, which has poor resection results similar to PHC, the criteria for resection have been established since 2004, and aggressive preoperative chemotherapy is used for “borderline resectable” cases. Those criteria have contributed to improved surgical outcomes. Similar criteria are required for PHC, but a consensus has not yet been reached on unresectable/resectable limits. In the future, it will be necessary to discuss what constitutes “borderline resectable” status based on investigations of poor prognostic factors after resection experienced by many institutions.
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