J.Jpn. Surg. Soc.. 99(11): 754-758, 1998

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Feature topic

RECENT ADVANCES IN LIVING-RELATED LIVER TRANSPLANTATION AND IN LIVER TRANSPLANTATION FOR PATIENTS WITH LIVER CIRRHOSIS AND HEPATOCELLULAR CARCINOMA

Livingrelated-donor liver transplantation has been performed in more than 700 patients in Japan. This article deals with recent advances in livingrelated-donor liver transplantation and the strategy for liver transplantation for patients with liver cirrhosis and hepatocellular carcinoma. The indication for livingrelated-donor liver transplantation has gradually widened to include urgent cases as well as adult patients. In livingrelateddonor Iiver transplantation for adults, limitation of graft volume has led to the use of left hepatic lobe grafts including the caudate lobe, or right hepatic lobe grafts. The results of liver transplantation for patients with hepatitis B cirrhosis, hepatitis C cirrhosis and hepatocellular carcinoma have improved, due mainly to advances in patient selection and perioperative medical care. The widespread use of liver transplants from both living and cadaveric donors is necessary in Japan, where adult patients with viral hepatitis and hepatocellular carcinoma account for the majority of patients with end-stage liver disease.

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