J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 337KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 93(1): 81-85, 1992

Original article

A CLINICAL STUDY OF THE SIGNIFICANCE OF THE GRADIENT BETWEEN FEEDING ARTERIAL TISSUE POLYPEPTIDE ANTIGEN (TPA) AND DRAINING VENOUS TPA IN ASSESSING THE RISK FOR RECURRENT BREAST CANCERS

1) Department of Surgery, School of Medicine, Shinshu University, Matsumoto, Japan
2) Department of Surgery, Iida City Hospital, Iida, Japan
3) Department of Surgery, Okaya Enrei Hospital, Okaya, Japan

Makoto Komatsu1), Osamu Senga2), Naoshi Hanamura3), Minoru Fujimori1), Shinya Kobayashi1), Akira Sugenoya1), Futoshi Iida1)

The incidence of postoperative recurrence of primary breast cancers in 73 patients was correlated with the blood levels of tissue polypeptide antigen (TPA) in peripheral veins (V-TPA), feeding arteries (A-TPA), draining veins (V-TPA) and the gradient between the TAP levels in draining veins and feeding arteries (V-A TPA).
With progression in the stage of the cancers, all parameters were increased. In stages II and III, the mean level of V-TPA was significantly higher than the mean level of A-TPA (p＜0.05). In each stage, each parameter was increased in the patients with recurrences when compared with the levels in the patients with no recurrences. In patients with V-A TPA gradients greater than 30 U/L, the rate of recurrence was significantly higher when compared with patients with gradients less than 30 U/L (p＜0.05).
The clinical significance of this finding is that patients with V-A TPA gradient greater than 30 U/L should be closely followed because of the increased risk of recurrences.

<< To previous pageTo next page >>

To read the PDF file you will need Adobe Reader installed on your computer.