[Abstract] [Full Text PDF] (in Japanese / 2208KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 92(7): 825-830, 1991


Original article

AUTOTRANSFUSION IN HEPATECTOMY FOR HEPATOCELLULAR CARCINOMA

First Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan

Jiro Fujimoto, Eizo Okamoto, Naoki Yamanaka, Takeshi Oriyama, Kazutaka Furukawa, Eisuke Kawamura, Tsuneo Tanaka

Experimental data of autotransfusion in hepatectomy for hepatocellular carcinoma and clinical data from forty-eight patients were analyzed. By a density gradient medium, cancer cells banded at a lower density (1.056g/ml: mean) than red blood cells (1.105g/ml: mean). The cenrifuge autotransfusor separated the red blood cells from cancer cells and all sections of cell blocks of the blood harvested intraoperatively in 20 cases revealed no malignant cells. The average requirement of bank blood was significantly reduced in these patients than in patients without autotransfusion during one year before, 1573ml to 478ml (whole blood of concentrated red blood cells) (p<0.05). These findings indicate that autotransfusion in hepatectomy for hepatocellular carcinoma is safe and practical.


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