J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 577KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 91(7): 883-888, 1990

Original article

A MULTIVARIATE ANALYSIS OF EN BLOC EXTENDED RADICAL MASTECTOMY VERSUS CONVENTIONAL RADICAL MASTECTOMY IN OPERABLE BREAST CANCER

1) The Operation Center, Kanazawa University Hospitl, Kanazawa, Japan
2) The Department of Surgery (II), Kanazawa University Hospitl, Kanazawa, Japan

Masakuni Noguchi1)2), Takao Taniya2), Naohiro Koyasaki2), Itsuo Miyazaki2)

We made clinical trials of en bloc extended radical mastectomy (EXT) of a new type in 118 patients from 1980 through 1985. Conventional radical mastectomies (RDL) were also performed in 105 patients from 1973 through 1985. A multivariate analysis was performed to compare the results of EXT and RDL. As the result, the 5-year survival rates of 91±2.6％ and 83±3.7％ were achieved for the EXT and RDL groups, respectively (Cox P value for comparison of survival curves＝0.16). Adjusted Cox regression analysis revealed a significantly favorable result of EXT (P＝0.03). This difference was most remarkable in patients with one to three metastatic axillary lymph nodes, although it was not statistically significant because of too small number of patients available (P＝0.18). The results are thus not definite, but suggest that EXT may be advantageous over RDL especially in patients with a few metastatic axillary lymph nodes.

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