J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 2235KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 90(7): 1043-1048, 1989

Original article

A ROLE OF SPLENECTOMY IN PATIENTS WITH HEPATOCELLULAR CARCINOMA AND HYPERSPLENISM AS AN AID TO HEPATECTOMY

Department of Liver Surgery, National Cancer Center Hospital, Tokyo, Japan

Tadatoshi Takayama, Masatoshi Makuuchi, Susumu Yamazaki, Hiroshi Hasegawa

To evaluate the clinical value of splenectomy for hepatic resection, a total of 20 patients with hepatocellular carcinoma and hypersplenism were examined focusing on a change of total serum bilirubin values after surgery.
Both hepatectomy and splenectomy were simultaneously performed in 12 patients, and in 8 patients as a staged operation. Postoperatively, a significant depression of bilirubin values was observed in a group with the preoperative values between 1.0mg/dl and 2.0mg/ml. Three factors (bilirubin, albumin and prothrombin time) in clinical stage were improved just after splenectomy with a statistical significance (p＜0.05) in a group received staged operation. In 7 out of 8 patients, clinical stages were getting better as one or two stages prior to the hepatectomies.
Therefore, we. recommend the addition of splenectomy to hepatectomy in the patients whose hyperbilirubinemia are assumed to be correlated with coexisting hypersplenism.

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