J.Jpn. Surg. Soc.. 90(3): 377-384, 1989
Original article
CHANGE OF GASTRIC MUCOSAL BLOOD FLOW AFTER SELECTIVE PROXIMAL VAGOTOMY； AN EXPERIMENTAL STUDY IN RATS
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Second Department of Surgery, Yokohama City University School of Medicine, Yokohama, Japan Shunji Eto |
The following results were obtained.
1) Resting MBF of the corpus decreased significantly from 106.3±9.8ml/min/100g to 74.5±15.5ml/min/100g at 12 weeks after SPV (p<0.01). Resting MBF of the antrum did not decrease.
2) Tetragastrin, betazol-HCI and 2-deoxy-d-glucose (2DG)-stimulated acid outputs were reduced following SPV for more than 12 weeks after operation.
3) The increase of corporal MBF after tetragastrin, betazol-HCI and 2DG stimulation was less significant with accompanying reduction of acid output.
4) The increase of antral MBF after tetragastrin or betazol-HCI stimulation was less significant after SPV. But, the increase after 2DG stimulation was as much as after SPV.
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