J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 3183KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 88(4): 483-488, 1987

Case report

SELENIUM DEFICIENCY AND CARDIOMYOPATHY IN A PATIENT ON LONG-TERM PARENTERAL NUTRITION

Department of Abdominal Surgery, Tenri Hospital, Tenri, Japan
*) Department of Medicine, Tenri Hospital, Tenri, Japan

Satoru Matsusue, Sadao Kashihara, Go Tomonaga*)

A 28 year-old Japanese male with Crohn's disease maintained on total parenteral nutrition for 5 consecutive years showed congestive cardiomyopathy. His symptoms (palpitation and precordial pain), arrhythmia on ECG and cardiomegaly on chest X-ray film were progressive. By intravenous selenium supplementation of 100μg/day (selenite) his symptoms disappeared dramatically and plasma selenium level, erythrocyte selenium level and glutathione peroxidase activity improved to normal ranges. It is suggested that this myocardial damage was caused by selenium deficiency.

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