J.Jpn. Surg. Soc.. 87(11): 1422-1425, 1986
Original article
STUDY OF CEA DOUBLING TIME OF LIVER METASTASIS FROM COLONIC CANCER AND POSTOPERATIVE SURVIVAL TIME
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Department of Surgery, Cancer Research Institute, Kanazawa University, Kanazawa, Japan Yutaka Takahashi, Satoru Kusama*), Masayoshi Mai, Masashi Ueno, Tomomi Ogino, Hiroshi Ueda, Kiyoshi Sawaguchi |
The doubling time of liver metastasis from colonic cancer ranged from 10 to 112 days (mean 57.8± 35.4days) was found significantly different among differentiations in histological type. Namely, the doubling time of poorly differentiated adenocarcinoma was shorter than that of well differentiated adenocarcinoma. Moreover the postoperative survival time (Y: months) was found to be significantly correlated with doubling time (X: days); Y=0.155X+4.452, r=0.718, p＜0.05. These results suggest that the growth rate calculated as CEA doubling time of cancer plays an important role in determining the degree of biological behavior in colonic cancer patients.
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