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J.Jpn. Surg. Soc.. 87(4): 456-463, 1986


Case report

A RESECTED CASE OF THE COLLISION TUMOR OF HEPATOCELLULAR CARCINOMA AND PRIMARY LIVER RHABDOMYOSARCOMA

The 2nd Department of Surgery, Fukui Medical School, Fukui, Japan
*) The Department of Central Laboratory, Fukui Medical School, Fukui, Japan

Hideki Morimoto, Yasutsugu Takada, Toshiaki Akita, Yoshinori Kato, Nobuhiko Tanigawa, Ryusuke Muraoka, Yoji Urata*)

Primary liver sarcoma is rare and especially its coexislence with hepatocellular carcinoma is extremely rare. We have collected eight cases of their coexislence in the literatures. The patient was a 62-year-old male complaining of right hypochondralgia and general malaise for about one month. CT scanning revealed the liver tumor and right hepatic lobectomy was performed. The tumor was sized in 14 by 9 by 9cm and composed of hepatocellular carcinoma and rhabdomyosarcoma, which were were collided. Apparent striations in the rhabdomyosarcoma cells was observed under light-microscope. Alphafetoprotein, of which serum level was extraordinally high, was detected only in hepatocellular carcinoma by special stains. He discharged one month after operation. He was readmitted due to recurrenee and received trans-arterial embolisation therapy and systemic chemotherapy. Though transient effect was obtained. he died forty-five days after operation. Autopsy revealed that recurrent liver tumors consisted of only hepatocellular carcinoma and that no other tumorous lesion was found in the other parts of the body. Rhabdomyosarcoma was proved to be primary tumor the liver.


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