[Abstract] [Full Text PDF] (in Japanese / 4677KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 86(12): 1646-1653, 1985


Original article

EFFECT OF AORTICORONARY BYPASS SURGERY ON LEFT VENTRICULAR FUNCTION AND CORONARY SINUS BLOOD FLOW IN PATIENTS WITH SEVERE LEFT VENTRICULAR DYSFUNCTION

*) First Department of Surgery, Osaka University Medical School, Osaka, Japan
**) Third Department of Surgery, Nara Medical College, Kashiwara, Japan

Tetsuo Sakakibara*), Hajime Hirose*), Susumu Nakano*), Hikaru Matsuda*), Kanji Kawachi**), Soichiro Kitamura**), Yasunaru Kawashima*)

Left ventricular function and coronary sinus blood flow were evaluated in 7 patients with severe left ventricular dysfunction at rest before and after aortocoronary bypass surgery, and during exeercise after surgery. Same evaluations were performed in 8 normal subject (G-C).
Cardiac index (CI) at rest (2.09±0.55l/min/m2) significantly increased after operation (2.94±0.59l/ min/m2) (p<0.02). There was no difference between CI during exercise afterr operation (5.94±1.51l/min/m2) and that in G-C.
Left ventricular end-diastolic pressure (LVEDP) at rest before operation (16±8 mmHg) was significantly higher than that in G-C (p<0.05). This difference disappeared after operation. LVEDP during exercise after operation (25±10mmHg) was significantly higher than that in G-C (p<0.01).
Coronary sinus blood flow (CSF) at rest (73±15ml/min) significantly increased after operation (123± 44ml/min) (p<0.02). There was no difference between CSF during exercise after operation (282±99ml/min) and that in G-C.
These deta indicated that the aortocoronary bypass surgery was effective on left ventricular function and coronary sinus blood flow in patients with severe left ventricular dysfunction.


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