J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 3517KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 86(1): 55-61, 1985

Original article

STUDIES ON AN ANTIGEN HIGHLY ASSOCIATED WITH HUMAN BRONCHO-GENIC SQUAMOUS CELL CARCINOMA（1）
－STUDIES BY IMMUNO-DIffUSION METHOD－

Department of Surgery (1), Kanazawa University School of Medicine, Kanazawa, Japan
*) Department of Pathophysiology, Cancer Research Institute, Kanazawa, Japan

Tetsuji Yamada, Yoh Watanabe, Hiroaki Kobayashi, Takashi Iwa, Shuji Okada*), Yoriaki Kurata*)

Insoluble extracts of human squamous cell carcinoma were solubilized by desoxycholate. The soluble extracts, after partial purification, were used to prepare antisera in guinia pigs. These antisera which were absorbed with insoluble extracts of lung, liver, kidney, spleen, carcinoembryonic antigen and non-specific cross-reacting antigen were commonly detected in all of the 7 squamous cell carcinomas. These antisera failed to reacted with adult organ extract, fetal organ homogenates or extracts from tumors of other histologic types by the methods of immuno-diffusion technique.

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