J.Jpn. Surg. Soc.. 84(12): 1269-1278, 1983
Original article
POSTPRANDIAL PLASMA SECRETIN CONCENTRATION AND LIUMINAL pH IN PATIENTS WITH GASTRECTOMY
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The First Department of Surgery, Osaka City University Medical School, Osaka, Japan Hideki Nishowaki, Katsusuke Satake, Teruo Kitamura, Kaoru Umeyama |
The fasting plasma secretin concentration was significantly elevated in relation to the decreases of doudenal pH in postprandial state in normal subjects. No significant response of the plasma secretin and jejunal pH were observed in patients with total gastrectomy with Roux-Y anastomosis, however total gastrectomized patients with jejunal interposition showed the peak plasma secretin response in postprandial state.
In patients with Billroth I the postprandial plasma secretin concentrations were well responsed when the duodenal pH was below 4.5, however it was less than that of normal subjects.
In patients with Billroth II the response of plasma secretin was much less than that of Billroth I, even though the decrease of jejunal pH was as comparable as in Billroth I.
These studies suggest that a Billroth I operation after subtotal gastrectomy and interposed jejunal anastomosis after total gastrectomy are better procedures than the Billroth II or Roux-Y anastomoses to obtain endogenous sectetin release.
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