J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 3177KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 84(6): 500-507, 1983

Original article

GENESIS AND EXTENSION OF INTRADUCTAL PAPILLOMAS OF THE BREAST
－A Three-Dimensional Morphological Study－

Second Department of Surgery, Tohoku University School of Medicine, Sendai, Japan
*) First Department Pathology, Tohoku University School of Medicine, Sendai, Japan

Noriaki Ohuchi, Rikiya Abe, Morio Kasai, Funiaki Tezuka*), Tohru Takahashi*), Masahisa Kyogoku*)

Graphic reconstruction of semi-serially sectioned breast specimens allowed a three-dimensional observation of intraductal proliferative lesions and their growth characteristrics. Ten surgical specimens with intraductal papollomas obtained by microdochectomy were subjected to this study, and the primary site and extending behavior of papillomas were analysed.
The results indicated: (1) In seven out of the ten cases papillomas appeared to arise from terminal duct lobular unit (TDLU) as multiple foci three-dimensionally independent of each other. (2) Secondary ductal involvement by multiple papillomas attained to as far as subsegmental or segmental level. (3) On the other hand solitary papilloma arose from segmental or subsegmental duct without involving TDLU. (4) Both solitary and multiple papillomas transformed and distorted the duct system while sustaining its basically arborescent pattern. (5) Duct papillomatosis, situated within TDLU, was often proved to be connected with multiple papillomas in more proximal ducts, and therefore was regarded as a prepapillomatous lesion. (6) Retension cysts associated with multiple papillomas were acounted for by intraductal proliferations obstructing outflow tracts.

<< To previous pageTo next page >>

To read the PDF file you will need Adobe Reader installed on your computer.