J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 2160KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 84(2): 135-140, 1983

Original article

MASSIVE HEPATIC RESECTION FOR METASTATIC CANCER ASSOCIATED WITH DUBIN-JOHNSON SYNDROME.
Report of a Case

1) Second Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan
2) Second Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Japan

Satoshi Nakamura1), Satoru Morioka1), Shozo Baba1), Matsuyoshi Maeda2), Hiroyuki Muro2)

Massive hepatic resection was carried out on a 42 year-old female who had metastatic lesions of the colonic cancer in right lobe of the liver, which was accompanied by Dubin-Johnson syndrome.
The following observations were made.
1) Patient with Dubin-Johnson syndrome tolerated major hepatectomy.
2) As for postoperative regeneration of the liver, there was no difference in comparison with the normal liver.
3) Dubin-Johnson pigments in the hepatocytes decreased in proportion to hepatic regeneration for two months after hepatectomy.
Therefore, it might be concluded that Dubin-Johnson syndrome is not poor risk factor for major surgery and massive hepatic resection.

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