J.Jpn. Surg. Soc.. 82(12): 1504-1515, 1981

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Original article

CLINCAL AND EXPERIMENTAL STUDY OF CELIAC AXIS COMPRESSION SYNDROME

Of seven caxes with celiac asis compression sydrome, D-xylose absorption was examined in four and only one showed impaired function. Decompression of the celiac axis in five cases resulted in weight gain and complete relief of pain in all cases. In order to clarify the hemodynamical change in this syndrome, the experimental model was made in mongrel dog.
1) Seventy per cent stenosis of the celiac axis produced rapid decrease in poststenotic flow and pressure, but these decreased significantly even at 50% stenosis with poststenotic vasodilatation.
2) In 60% stenosis of the celiac axis, bypass graft was implanted between superior mesentric and splenic artery. In this condition, the induced poststenotic vasodilatation increased the flow of common hepatic and superior mesenteric artery to 150% and 117%, respectively. On the contrary, the blood flow in jejunal wall decreased to 68%.
3) Impaired absorption of D-xylose induced by 80% celiac axis stenosis improved after three months, followed by the development of collaterals.
4) These results suggested that postprandial mesenteric ischemia may develop in this syndrome and induce an abdominal pain. Therefore, it is deduced that weight loss in this syndrome is not due to malabsorption, but to limitation of diet intake because of fear to postprandial abdominal pain.

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