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J.Jpn. Surg. Soc.. 114(5): 232-235, 2013


Feature topic

EFFECTIVENESS AND MOTION MECHANISM OF TAIKENCYUTO IN THE PERIOPERATIVE PERIOD

1) Department of Surgery, Fujita Health Univeristy, Japan
2) Advanced Surgery Center, Sapporo Higashi Tokusyuukai Hospital, Sapporo, Japan

Koutarou Maeda1), Hidetoshi Katsuno1), Toru Kono2)

Taikencyuto (TJ-100) is a Japanese herbal (Kampo) medicine that contains Zanthouxylum and piperitum, Zingiber officinale, Panax ginseng, and Saccharum granorum. TJ-100 enhances intestinal motility, is thought to promote acetylcholine and motilin release, and is a vanilloid receptor. Furthermore, TJ-100 increases intestinal blood flow and works as an antiinflammatory and anticytokine agent by producing calcitonin gene-related peptide and adrenomedullin. TJ-100 is considered to be useful for promoting intestinal motility and preventing ileus during the perioperative period. Further studies must be performed to confirm its usefulness in perioperative care.


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