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J.Jpn. Surg. Soc.. 125(5): 430-434, 2024
Feature topic
DEESCALATION OF AXILLARY SURGERY
Currently, the standard axillary surgery for breast cancer is axillary lymph node dissection up to level II for patients with clinically evident positive axillary lymph nodes. Sentinel lymph node biopsy (SNB) is the standard procedure for clinically node-negative cases. Since the report of ACOSOG Z0011, clinical trials investigating deescalation of axillary surgery have been rapidly planned. In particular, the efficacy of SNB for clinical node-positive cases with preoperative chemotherapy has been reported from several studies; in 2023, the safety of omitting SNB for cN0 cases was reported (SOUND trial). Clinical trials of axillary deescalation for patients with positive clinical lymph nodes are ongoing.
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