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J.Jpn. Surg. Soc.. 111(4): 268-274, 2010
Case report
PRESENT STATUS OF PEDIATRIC LIVING-DONOR LIVER TRANSPLANTATION
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1) Transplantation Surgery, National Center for Child Health and Development, Tokyo, Japan Mureo Kasahara1), Seisuke Sakamoto1), Takanobu Shigeta1), Akinari Fukuda1), Naoto Matsuno1), Hideaki Tanaka2), Yoshihiro Kitano2), Tatsuo Kuroda2) |
Subjects and methods: We have done 103 cases of LDLT during November 2005 through September 2009 in National Center for Child Health and Development. Variables including indication of liver transplantation/infectious/immunological outcome were reviewed.
Results: The indication for liver transplantation was cholestatic liver disease in 43.76%, followed by metabolic liver disease 24.3% and acute liver failure 18.5%. The mean age of recipient was 3.6±4.2years and body weight was 14.4±11.1kg. Immunosuppression consisted of tacrolimus and low-dose steroids. The incidence of acute cellular rejection was 33.3%. The graft and patient survival were 92.2%.
Conclusion: Satisfactory result can be achieved on LDLT program in National Center for Child Health and Development. The follow-up period was too short to make definitive conclusion, however, long-term observation may be necessary to collect sufficient data for the establishment of the treatment modality.
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