J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text HTML] [Full Text PDF] （in Japanese / 439KB） [Members Only]

J.Jpn. Surg. Soc.. 111(4): 268-274, 2010

Case report

PRESENT STATUS OF PEDIATRIC LIVING-DONOR LIVER TRANSPLANTATION IN NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT

1) Transplantation Surgery, National Center for Child Health and Development, Tokyo, Japan
2) Pediatric Surgery, National Center for Child Health and Development, Tokyo, Japan

Mureo Kasahara1), Seisuke Sakamoto1), Takanobu Shigeta1), Akinari Fukuda1), Naoto Matsuno1), Hideaki Tanaka2), Yoshihiro Kitano2), Tatsuo Kuroda2)

Purpose: We reviewed our initial experience of pediatric living-donor liver transplantation (LDLT) in National Center for Child Health and Development and report the results herein.
Subjects and methods: We have done 103 cases of LDLT during November 2005 through September 2009 in National Center for Child Health and Development. Variables including indication of liver transplantation/infectious/immunological outcome were reviewed.
Results: The indication for liver transplantation was cholestatic liver disease in 43.76%, followed by metabolic liver disease 24.3% and acute liver failure 18.5%. The mean age of recipient was 3.6±4.2years and body weight was 14.4±11.1kg. Immunosuppression consisted of tacrolimus and low-dose steroids. The incidence of acute cellular rejection was 33.3%. The graft and patient survival were 92.2%.
Conclusion: Satisfactory result can be achieved on LDLT program in National Center for Child Health and Development. The follow-up period was too short to make definitive conclusion, however, long-term observation may be necessary to collect sufficient data for the establishment of the treatment modality.

<< To previous page

To read the PDF file you will need Adobe Reader installed on your computer.