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J.Jpn. Surg. Soc.. 106(7): 413-417, 2005


Feature topic

TREATMENT STRATEGY OF MALIGNANT SOLID TUMORS IN CHILDHOOD

Pediatric Surgical Department, Chiba University Graduate School of Medicine, Chiba, Japan

Naomi Ohnuma, Hideo Yoshida, Tadashi Matsunaga, Katsunori Kouchi, Tomoro Hishiki, Shinichi Yamada, Yoshiharu Satoh, Keita Terui

The prognosis for children with malignant solid tumors has improved dramatically in Japan.
During the last two decades, various groups have conducted sequential studies of the treatment of children with neuroblastoma, Wilms’tumor, and hepatoblastoma. Most institutes participated in nonrandomized trials designed to evaluate the safety and efficacy of combination chemotherapy, surgery, and radiotherapy in each group study and treated children with these tumors. The results are reviewed and areas for future investigation are identified.


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