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[Members Only] J.Jpn. Surg. Soc.. 106(1): 18-22, 2005
Feature topic
PLASMA PROTEIN DERIVATIVES
Plasma protein derivatives produced from human plasma include albumin, blood coagulation factors, immuno globulins, haptoglobin, and c
1-inactivator and have been widely used clinically. However, the HIVtainted blood scandal, in which HIV was transmitted to many Japanese patients through blood coagulation factors, must be remembered. The safety of blood products has increased since then in response to that event. Because blood products are provided by volunteer donors, there is a risk of contamination by unknown pathogens and they must be used appropriately. In addition, blood products including plasma derivatives are defined as “special biological products” and regulated by the new Medicine Act. All physicians who prescribe plasma derivatives should understand not only their clinical use but also social expectations and legal regulations.
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