J.Jpn. Surg. Soc.. 105(8): 430-434, 2004

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Feature topic

BIOMEDICAL RESEARCH FRONTIER FOR REGENERATIVE MEDICINE

Making much of self-renew potential of the llving body, “Regenerative Medicine" is sure to play an essential role providing an innovation in treating many human disorders. Although there has been remarkable advances in this field, they are successful only in certain tissues such like vessels or bone/cartilage. When think about the solid organs, i.e. liver or pancreas, it still remains as a huge research frontier. By combining the usage of flow-cytometry and fluorescence-labeled monoclonal antibodies, we had established an elegant methodology of single cell isolation which opened up the way to challenge this “frontier" and it finally led us to the success in identifying/characterizing the stem cells in such organs. Now our research enterprise covers through further understanding of the core stem cell biology to the development of basic technology to realize “Regenerative Medicine" so that we will be able to get reach the achievement to meet the increasing demands of patients suffering these tissues and organs.

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