[Abstract] [Full Text PDF] (in Japanese / 1684KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 103(8): 538-542, 2002


Feature topic

SURGICAL TREATMENT FOR ADVANCED GALLBLADDER CANCER:INDICATIONS AND LIMITATIONS

Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan

Katsuhiko Uesaka, Naokazu Hayakawa, Junichi Kamiya, Satoshi Kondo, Masato Nagino, Michio Kanai, Tsuyoshi Sano, Toshiyuki Arai, Norihiro Yuasa, Koji Oda, Hideki Nishio, Yuji Nimura

We have aggressively performed extensive surgery including major liver resection for advanced gallbladder cancer since 1979. The 5-year survival rates for stage IVa and IVb patients after curative resection were 19% and 6%, respectively. Seven patients in the stage IVa group (n=69) and one in stage IVb (n=16) have survived for more than 5 years. The hospital mortality rate including all deaths within and over 30 days of curative operation for stage IV gallbladder cancer was 19%.
Although radical resection is the only treatment of choice for advanced gallbladder cancer to obtain longterm survival, there are serious problems in extensive surgery. The most important issue is reduction of the hospital mortality rate. Elucidation of the clinical and molecular characteristics leading to potential long-term survival and development of new strategies for the treatment of recurrent tumors are also important issues.


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