J.Jpn. Surg. Soc.. 100(3): 249-256, 1999

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Feature topic

TREATMENT OF BARRETT'S ESOPHAGEAL CANCER, WITH SPECIAL REFERENCE TO ENDOSCOPIC TREATMENT

Most cases of Barrett’s esophageal cancer are discovered in the advanced stage, and there fore the principle treatment is surgical. Endoscopic treatment is employed for patients with early cancer and severe dysplasia discovered by endoscopic examination, accidentally or during follow-up of Barrett’s esophagus.
Among the endoscopic forms of treatment, photodynamic therapy (PDT) is the main proceedure for early cancer and severe dysplasia in Barrett’s esophagus. Recently argon plasma coagulation (APC) has been introduced for the treatment of severe dysplasia and early cancer, in addition to Barrett’s epithelium itself. In Japan, endoscopic mucosal resection (EMR) has also been employed in 5 cases of mucosal canser in Barrett’s esophagus. It will be used more widely in Japan, because the number of reflux esophagitis and Barrett’s esophagus cases will increase in the near future.

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