J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 958KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 100(2): 211-215, 1999

Feature topic

TREATMENT OF POSTOPERATIVE RECURRENCE OF DIGESTIVE CANCERS : PERITONITIS CARCINOMATOSA

1) First Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
2) Tokyo Metropolitan Komagome Hospital, Tokyo, Japan

Toshiharu Yamaguchi1), Toshio Takahashi2), Kiyoshi Sawai1), Akeo Hagiwara1), Hiroki Taniguchi1), Kazuya Kitamura1), Eigo Otsuji1), Chohei Sakakura1), Morio Shirasu1), Kazuma Okamoto1), Hisakazu Yamagishi1)

Carcinomatous peritonitis is the most frequent type of recurrence observed after surgery for cancer of the digestive tract. Most patients with carcinomatous peritonitis present with bowel obstruction and/or ascites. Surgical treatment including colostomy and intestinal anastomosis and chemotherapy have been attempted in patients with carcinomatous peritonitis, although the results have not been satisfactory. New drug delivery systems, such as mitomycin C-adsorbed charcoal, anticancer drugs entrapped in microspheres, and immunoconjugates composed of anticancer drugs and antibodies, will be powerful new tools for the treatment of metastatic cancer.

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