J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 1727KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 98(1): 68-70, 1997

Case report

A CASE WITH THYROID CARCINOMA ASSOCIATED WITH FALSELY INCREASED TSH VALUES

Second Department of Surgery, Faculty of Medicine Tottori University, Tottori, Japan

Kaoru Kobayashi, Hiroyuki Maeta, Tasuku Honda, Yoshiyuki Tanaka, Tohru Mori

A 63-year-old woman with papillary thyroid carcinoma showed increased TSH values (measured by two-site immunometric assay kit). X-ray and endocrinological examinations did not prove the coexistence of pituitary neoplasm. TSH values which were measured by using an another TSH assay system (TSH RIABEAD II assay kit) revealed normal range. Measured TSH values were reduced by adding mouse IgG into seurm. These findings suggest that substances in serum, which can link reagent mouse antibody in the assay system, may give falsely increased TSH values.
We should be awre that two-site immunometric assay may give falsely increased hormone values due to the appearance of substances against anti-animal antibodies in serum.

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