J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 819KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 96(6): 402-405, 1995

Case report

A CASE OF PRIMARY PULMONARY B CELL LYMPHOMA COMFIRMED BY GENE ANALYSIS

1) Department of Respiratory Division, Akaho Municipal Hospital, Akaho, Japan
2) Department of Surgery, Akaho Municipal Hospital, Akaho, Japan

Tetshiro Shiota1), Masaki Kanaoka1), Shinichi Oshima2), Satoshi Kaibara2), Kimio Henmi2)

A 76-year-old man visited our clinic with chest radiographic evidence of a coin lesion in the right middle Iung. Chest CT demonstrated an infiltrative shadow mainly in the S4 segment. Lymphoproliferative disorders were suggested by transbronchial lung biopsy. Middle lobectomy was performed. Pathological study showed massive proliferation of mature lymphocytes. Immunoperoxidase studies could not demonstrate a neoplastic monoclonal process. Pseudolymphoma was diagnosed. High molecular weight DNAs were extracted from frozen specimens. Whether genes of immunoglobulins and T-cell receptors were rearranged was investigated using DNA probes against JH and TCRβ-1 receptor gerle. One rearranged band was found in the JH chain. No rearranged band appeared in TCRβ-1 chain. B cell lymphoma was diagnosed instead of pseudolymphoma.

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