J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 485KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 95(6): 394-399, 1994

Original article

LONG-TERM RENAL FUNCTION AFTER NEPHRECTOMY IN LIVING RELATED KIDNEY DONORS

1) Second Department of Surgery, Tohoku University School of Medicine, Sendai, Japan
2) Sendai Shakahikoken Hospital, Sendai, Japan

Koichiro Sato1), Susumu Satomi1), Nobuhiro Ohkohchi1), Hiroshi Shibuya1), Hajime Okazaki2), Yoshio Taguchi1), Shozo Mori1)

The purpose of this study is to evaluate the long-term renal function of donors after nephrectomy in living related renal transplantation (n=100). The survival rate of donors was 98% and causes of death in the other 2% were not associated with the donation. Serum creatinine (Ser) and Creatinine clearance (Ccr) deteriorated just after the donation, but gradually improved. The number of donors with proteinuria increased after donation. In Ser and Ccr there was no significant difference between donors with and without proteinuria. In the donors with hypertension (25.3%) mean urine protein was higher than in those without hypertension. There was a correlation between systolic blood pressure and proteinuria. These results strongly suggest that renal function of donors deteriorates once just after the donation, but gradually improves year by year, and that hypertension is strongly associated with renal dysfunction, especially proteinuria, after the donation.

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