J.Jpn. Surg. Soc.. 94(8): 840-846, 1993

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Original article

EVALUATION ON OUR PROCEDURE FOR AUTOTRANSPLANTATION OF PARATHYROID GLANDS BY THE INTACT-PTH

In thyroid cancer surgery since 1978 we have made parathyroidal autotransplantation which has been to resectthe entire parathyroid, cut fine to mud and autotransplant into greater pectoral muscle. To evaluate ourprocedure and consider the mechanism of hypocalcemia and tetanus following surgery, we examined the intact-PTH recovered to about 80% of its preoperative value on 14-postoperative-days and thereafter remained almostconstant. It remained below the sensitivity of measurement from immediately to 3-postoperative-days, and withour procedure, parathyroid was considered to be totally resected. Comparison between 2 (6 cases) and moreautotransplanted glands (11 cases) revealed that the former showed slightly later functional recovery, butrecovered to the almost some extent as the other 21-postoperative-days. Comparison between the group requiringcalcium supplement therapy (12 cases) and the otherwise (5 cases) revealed almost the same course ofrecovery. Thus, our procedure seems to enable us to make satisfactory functional preservation and expectfunctional recovery by 2-gland autotransplantation at least. The supplement therapy was considered not to bedetrimental to the take of autotransplanted glands and functional recovery, and no correlation was noted between the onset of tetanus and intact-PTH.

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