J.Jpn. Surg. Soc.. 93(7): 675-683, 1992
Original article
POSTOPERATIVE CHANGES OF ACUTE PAHSE PROTEIN IN PATIENTS WITH ESOPHAGEAL CANCER
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The First Department of Surgery, Kagoshima University School of Medicine, Kagoshima, Japan Kazusada Shirao, Chikara Kusano, Shoji Natsugoe, Heiji Yoshinaka, Toshitaka Fukumoto, Takashi Aiko, Hisaaki Shimazu |
Significant Spearman's coefficients were found between percent of ideal body weight (IBW) and α1-acid glycoprotein (r=－0.42), between prealbumin and α1-anti-trypsin (r=－0.55), and between retinol-binding protein and α1-antitripsin (r=－0.51).
Postoperatively, the levels of C-reactive protein, fibrinogen, α1-anti-trypsin and α1-acid glycoprotein were significantly lower in the poorly nourished group than in the other groups. The changes of acute phase proteins in the immediate postoperative period were affected by the preoperative nutritional state, and were less marked in the poorly nourished patients. Between two groups of patients in whom lymph node dissection was carried out in 2 or 3 areas, no significant differences were observed in the acute phase protein responses postoperatively.
The mearsurement of acute phase proteins is very important in assessing the body defense capacity of the patient, but it should be noted that the changes may be affected by several factors including malnutrition.
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