J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 565KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 93(5): 553-555, 1992

Case report

LOCAL RECURRENCE OF DIFFERENTIATED THYROID CARCINOMA EFFECTIVELY TREATED BY LOCAL INJECTION OF OK-432

Department of Surgery, School of Medicine, Keio University, Tokyo, Japan

Ryoichi Kato, Teruhisa Kobayashi, Masazumi Watanabe, Masafumi Kawamura, Koji Kikuchi, Koichi Kobayashi, Tsuneo Ishihara

Local recurrence of differentiated thyroid carcinoma in a 67-year-old woman was treated by topical injection of OK-432 every 2-4 weeks. Recurrent tumors tumed into small scar-like tissues after 9 months of OK-432 administration. The bleeding from the tumor was well controlled. Secondary recurrent tumors were also effectively treated in the same manner. About 2 years have passed since the start of the treatment and the local recurrence is well controlled. We conclude that topical injection of OK-432 might be a good modality of treatment for the local recurrence of thyroid carcinoma.

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