J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 358KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 93(2): 208-211, 1992

Case report

AN AUTOPSIED CASE OF PAPILLARY THYROID CARCINOMA SHOWING DNA HETEROGENEITY-COMPARISON OF DNA CONTENT BETWEEN PRIMARY FOCUS AND METASTATIC FOCUS

1) Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan
2) Department of Pathology, Shinshu University School of Medicine, Matsumoto, Japan

Makoto Komatsu1), Shinya Kobayashi1), Akira Sugenoya1), Hiroyuki Masuda1), Shozo Takahashi1), Futoshi Iida1), Nobuo Ito2)

A 56-year-old female case of papillary thyroid carcinoma is reported. Nuclear DNA analysis using flow cytometry and immuno-histological staining with thyrogloburin, CA19-9 and CA125 of the primary and metastatic foci from the autopsy specimens were performed. Correlation between ploidy patterns and immuno-histological staining was not found. Although two histogram patterns namely DNA diploid (DP) and aneuploid (AP) with DNA index of 1.3 were seen in primary, sternal and lung metastatic foci, only DP pattern was seen in the lymph node metastatic foci.

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