[
Abstract]
[
Full Text PDF] （in Japanese / 3369KB）
[Members Only And Two Factor Auth.] J.Jpn. Surg. Soc.. 91(8): 942-949, 1990
Original article
EFFECT OF POSTOPERATIVE HYPERTONIC SODIUM INFUSION IN THE PATIENTS WITH TOTAL GASTRECTOMY FOR GASTRIC CANCER
In 17 patients with gastric cancer undergoing total gastrectomy, the effect of postoperative hypertonic sodium infusion were studied. The subjects were divided into 2 groups by concentration in the postoperative infusions. Group 1 (Na group): over 5.0mEq/Kg/day of sodium were infused in the postoperative days (POD). (End of operation to POD-4), Group 2 (Control group): 2.0－2.5mEq/Kg/ day of sodium (End of Op. to POD-1), 1.5－2.0mEq/Kg/day (POD-2－4). 2.0－2.5mEq/Kg/day were infused after POD-5 in both groups. In the Na group, NAG-lndex, FENa and BUN were higher than those of control group. And cumulative primary Na balance (from end of operation to POD-5) indicated positive balance in Na group, and negative in control group. Futhemore, the cumulative infused sodium dose correlated with cumulated urinary sodium dose, potasium dose and cumulative NAG dose (from end of operation to POD-5). Significant difference was observed between two groups in urinary nitrogen. These findings suggest that the sodium dose in the postoperative infusion were suitable with 2.0－2.5 mEq/Kg/day.
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