J.Jpn. Surg. Soc.. 90(10): 1718-1721, 1989
Original article
BROMODEOXYURIDINE LABELING INDEX IN GASTRIC CANCER
|
The Second Department Surgery, Kanazawa University School of Medicine, Kanazawa, Japan Toru Kamata, Yutaka Yonemura, Kazuo Sugiyama, Shigekazu Ooyama, Takeo Kosaka, Koichi Miwa, Ituo Miyazaki |
A comparison of the in vitro and in vivo L.I. showed good correlation (p＜0.01). Gastric cancer with lymph node metastasis had a significantly higher median in vivo L.I. of 16.2% as compared with a median in vivo L.I. of 13.3% in gastric cancer without lymph node metastasis (p＜0.05). An in vivo L.I. of gastric cancer with vessel invasion was significantly higher than that without vessel invasion (p＜0.05). Early gastric cancer with an in vivo L.I. of less than 12% had no lymph node metastasis. On the contrary, 31% in that with an in vivo L.I. of greater than 12% had lymph node metastasis.
The in vitro L.I. which was similar to the in vivo L.I. may be useful to decide operative procedure in gastric cancer, specially in early gastric cancer.
To read the PDF file you will need Adobe Reader installed on your computer.