J.Jpn. Surg. Soc.. 90(8): 1140-1153, 1989

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Original article

A STUDY ON AMINO ACID SOLUTIONS FOR POSTOPERATIVE PARENTERAL NUTRITION
ーEVALUATION IN TERMS OF SURGICAL STRESS, AMINO ACID COMPOSITION AND ITS DOSESー

A newly composed amino acid solution, which contained a 30%branched-chain amino acid (BCAA), and a standard amino acid solution containing 22.6% BCAA were used for total parenteral nutrition following operation of the digestive organs. Their nutritional effects were evaluated by surgical stress (thoracotomy group or non-thoracotomy group) according to the two steps of amino acid doses (1.2g/kg/day administration group or 1.6g/kg/day group).
1. No significant differences could be recognized in an improvement in the serum proteins following administration of BCAA-enriched solution either in the thoracotomy or in the non-thoracotomy group.
2. An improvement in BCAA/AAA molar ratio was seen on the plasma aminogram following administration of BCAA-enriched solution both in the thoracotomy and in the non-thoracotomy groups.
3. No improvement in nitrogen balance following administration of BCAA-enriched solution could be found in the thoracotomy group, while its improving trend was recognized in the non-thoracotomy group treated with 1.6g/kg/day of the amino acid.
4. Neither in the thoracotomy nor in the non-thoracotomy group any significant inhibition of the excreted volumes of urinary 3-methylhistidine could be recognized.

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