[Abstract] [Full Text PDF] (in Japanese / 353KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 89(2): 251-255, 1988


Original article

IN VIVO MEASUREMENTS OF ELECTRICAL BIO-IMPEDANCE OF BREAST TUMORS

*) The Second Department of Surgery, School of Medicine, The University of Tokushima, Tokushima, Japan
**) Department of Electric Engineering, Faculty of Engineering, The University of Tokushima, Tokushima, Japan
***) Department of Electric Engineering, Technical College, The University of Tokushima, Tokushima, Japan

Nanretsu Mitsuyama*), Tadaoki Morimoto*), Yohsuke Kinouchi**), Tadamitsu Iritani***), Takanao Sumi*), Suguru Kimura*), Yasumasa Monden*)

The electrical bio-impedance of 17 breast tumors including 12 breast cancers and 5 fibroadenomas,were measured in vivo with three-electrode method in the frequency range of 0 to 200 KHZ. The three-electrode consists of a coaxial needle electrode inserted into the tumor and a large reference electrode on upper abdominal wall.
The tissue can be regarded electrically as a equivalent consisted of extracellular resistance (R1), intracellular resistance (R2), and electric capacitance of the cell membrane (C). These three parameters were calculated from the measured values of electrical bioimpedance. It was found that R1, and R2 of breast cancers were significantly higher than those of fibroadonomas (p<0.001), and that C of breast cancers was significantly lower than that of fibroadenomas (p<0.001). The measurement of the electrical impedance of breast tumor in vivo may be useful for the differencial diagnosis of brest lesions.


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