J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 2297KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 89(1): 30-38, 1988

Original article

LOCALIZATION OF ENOLASE IN THE CANCER NEST OF DIGESTIVE ORGANS

*) Surgical Department, Kariya General Hospital, Kariya, Japan
**) Department of Biochemistry, Institute for Developmental Research, Aichi Prefectural Colony, Kasugai, Japan
***) Pathological Department , Aichi Cancer Center, Nagoya, Japan

Shizuo  Usami*), Shusaku Hayashi*), Takashi Ohkubo*), Hikozo Kotani*), Kanefusa  Kato**), Hajime Haimoto***)

γ-Enolase, otherwise called neuron specific enolase (NSE), is specific for neural and neuro-endocrine systems and is present in the tumor s of these systems. γ-Enolase is also reported to be present, however, in a localized form in the tissues of other nonneural systems in some cases of lung cancer in relatively large number of incidences.
We examined immunohistologically specimens of digestive organ cancers. Two principal conclusions were obtained. First, γ-enolase is not specific for neural and neuro-endocrine systems. Second, γ-enolase is localized in the epithelium of cancers of some cases following the transformation into cancer.

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