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J.Jpn. Surg. Soc.. 87(11): 1485-1490, 1986


Case report

FIBROLAMELLAR CARCINOMA OF THE LIVER : A CASE REPORT

The First Department of Surgery, Jikei University School of Medicine, Tokyo, Japan

Kazuhiko Yoshida, Susumu Kobayashi, Sakae Miyamoto, Juemon Kudo, Kimitoshi Hachiya, Shuzo Inada, Kenji Sakurai

This is the first case report of fibrolamellar carcinoma of the liver (FCL) in Japan with reference to the relevant literature.
A 56 year-old Korean male with positive HBsAg was complaining of generalized weakness. Alfafetoprotein level was elevated and a mass lesion in right lobe of the liver was detected. He underwent a wedge resection, of the liver and the follow-up study failed to show recurrence of the tumor in 15 months. The specimen showed a tumor consisting of a firm, grayish-white, circumscribed solitary mass measuring 4cm in diameter. Microscopically the tumor was characterized by polygonal and eosinophilic tumor cells and abundant fibrous stroma around the tumor cells in lamellar fashion. FCL is a well defined disease entiry with a distinct histologic pattern and a favorable prognosis.


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