J.Jpn. Surg. Soc.. 87(11): 1443-1448, 1986
Original article
MEASUREMENT OF PANCREATIC MICROCIRCULATION OF DOG BY USING HYDROGEN GAS GENERATED BY ELECTROLYSIS IN DOG
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The First Department of Surgery, Osaka City University medical School, Osaka, Japan Hideki Nishiwaki, Katsusuke Satake, Ichikun Ko, Hajime Tanaka, Gakushu Kanazawa, Yuji Nagai, Kaoru Umeyama |
After Iaparatomy under general anesthesia, uncinate process of the pancreas was punctured by a needle electrode for electrolysis and determination of hydrogen gas. The consecutive measurements of pancreatic microflow revealed the good reproducibility at the same point of the pancreas. The simultaneous measurements of pancreatic microflow by electrolysis and pancreatic tissue blood flow by H2 inhalation method were carried out at the same point of the pancreas.
Correlation analysis of both measurements revealed coefficient of 0.751 and a significant relationship was observed (p＜0.05). However, the value was a little higher in pancreatic microflow as compared with pancreatic tissue blood flow.
Pancreatic microflow and pancreatic exocrine secretion increased after intravenous administration of Dopamine and Secretin (10μg/kg/min).
It is concluded that the measurement of pancreatic microflow by hydrogen gas generated by electrolysis is a useful method on understanding the microcirculation of the pancreas.
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