J.Jpn. Surg. Soc.. 87(1): 20-28, 1986
Original article
HUMAN CHORIONIC GONADOTROPIN-LIKE SUBSTANCE (hCGLS) IN MALE PATIENTS WITH GASTROINTESTINAL CANCER
|
The First Department of Surgery, School of Medicine, Chiba University, Chiba, Japan Yoshiaki Ohyama |
Elevated serum hCGLS levels were observed in 6/8 (75％) of male patients with early gastric cancer, 14/22 (63.7％) with resectable, 4/10 (40％) with unrescetable gastric cancer and 10/13 (76.7％) with resectable colorectal cancer. In benign diseases none had an elevated level in serum hCGLS. Serum hCGLS levels showed a declining tendency with progress of disease as well as with low histologic differentiation.
HCGLS levels in gastric and colorectal cancer tissues were significantly higher than those in normal mucosal tissue.
There were no correlation between hCGLS and β-subunit hCG levels in serum as well as in cancer tissue. Correlation between not only hCGLS and CEA levels in cancer tissue but also hCGLS tissue levels and tumor size was observed in colorectal cancer, while not in gastrIc cancer.
Thus, hCGLS may be of practical value in complementary diagnosis of male gastrointestinal cancer.
To read the PDF file you will need Adobe Reader installed on your computer.