J.Jpn. Surg. Soc.. 86(12): 1632-1639, 1985
Original article
THE EFFECTS OF INTRA-ABDOMINAL PRESSURE ON REGIONAL RENAL BLOOD FLOW DURING PERITONEAL DYALYSIS
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Second Department of Surgery, Miyazaki Medical College, Miyazaki, Japan Toshio Onitsuka, Yasunori Koga, Koichiro Shibata, Takami Maeda, Kiyoshi Ishii, Yasunori Matsuzaki, Kunihide Nakamura |
The mongrel dogs were divided into four groups.
Group I (n=10) : IAP of atomospheric pressure without PD (control group)
Group II (n=10) : Intermittent PD with IAP of 10mmHg
Group III (n=10) : Intermittent PD with IAP of 20mmHg
Group IV (n=10) : Continuous PD with IAP of 3-5mmHg
The following results were obtained.
1) Significant decrease (p＜0.01-0.05) of renal cortical blood flow (RCBF), total renal blood flow (TRBF), ratio of RCBF to renal medullar blood flow, renal perfusion pressure (RPP), cardiac index and urinary output, and increased renal vascular resistance and inferior vena caval pressure were observed in group III, but in group IV, values of these parameters returned to control level.
2) The limit of influence to renal function was confirmed to be as follows. (1) IAP of 30mmHg or more, (2) RPP of less than 65mmHg, (3) TRBF of less than 2.2ml/g/min, (4) and RCBF of less than 78ml/100g/min.
3) These studies suggest that RPP are simple and excellent index to reflex renal hemodynamics, and the continuous PD are better procedure than the intermittent PD from a view of renal regional blood flow.
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