[
Abstract]
[
Full Text PDF] (in Japanese / 1598KB)
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J.Jpn. Surg. Soc.. 85(8): 758-762, 1984
Original article
PRESERVATION OF THE NIPPLE AND AREOLA FOR BREAST CANCER
―HISTOPATHOLOGICAL STUDY ON CANCEROUS INVOLVEMENT OF THE NIPPLE AND AREOLA―
In 141 mastectomy specimens, performed for invasive or non-invasive carcinomas, histopathologic study was performed to assess the extent of nipple-areola involvement by the tumor. In this study, patients were excluded when 1) the tumor was located beneath the areola, 2) nipple and/or areola abnormalities were clinically present. Tumor involvement of the nipple and/ or areola was found in 44 of 141 specimens (31%), with intraductal growth in 36 (82%) of 44, stromal invasion in 3 (7%) and ductal & stromal invasion in 5 (11%). Analysis of nipple-areolar involvement with consideration of the different variables indicates that it occurred in association with tumor size, tumor-areola distance and histological type. Such information provides clinically relevant guide lines in decision making for limited breast surgery.
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