[Abstract] [Full Text PDF] (in Japanese / 3100KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 84(12): 1286-1290, 1983


Original article

PATHOGENESIS AND PREVENTION OF THE REVASCULARIZATION SYNDROME

Department of Surgery, Nagoya University Branch Hospital, Nagoya, Japan
*) College of Medical Technology, Nagoya University, Nagoya, Japan

Junichi Matsubara, Takashi Ohta, Masafumi Hirai, Shigehiko Shionoya, Ichiro Ban*)

Revascularization syndrome is one of the dangerous postoperative complications which results sometimes in loss of a limb, renal shutdown and death due to myoglobin-nephrosis and hyperkalemia.
During the past 3 years, 2 cases of revascularization syndorme were experienced in 16 cases of thrombo-embolectomies for acute peripheral arterial occlusion. One patient died from hyperkalemia 100minutes after revascularization. Another patient suffered from a renal suhutdown, and was treated with hemodialysis and thigh amputation.
It is sometimes very difficult to predict whether the revascularization syndrome will occur or not.
When revascularization is performed within 12 hours after an onset of acute occlusion and when the amount of ischemic muscle is not large, the syndrome may not occur.
When the time-interval between the onset of ischemia and revascularization is longer than 24 hours and when the mass of ischemic muscle is large, the syndrome will occur. Preoperative serum creatinine and urea nitrogen level are important parameters predicting the prognosis.


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