J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 3346KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 84(4): 271-281, 1983

Original article

EFFECT OF FAT EMULSION (INTRALIPID) ON ESSENTIAL FATTY ACID DEFICIENCY DURING TOTAL PARENTERAL NUTRITION IN PEDIATRIC PATIENTS
Part 1. Experimental study

First Department of Surgery, Chiba University Medical School, Chiba, Japan

Tsuguhiko Tashiro, Yoshiya Mashima, Katsuji Okui

Experimental studies were performed to confirm the effect of TPN with and without fat emulsion, Intralipid, on fat metabolism in weanling rats and puppies.
1) Long-term fat-free TPN induced essential fatty acid (EF A) deficiency in weanling rats and the intravenous fat emulsion which accounted for 10% of the total caloric intake could prevent EFA deficiency.
2) In the long-term TPN in growing puppies, fatfree TPN induced EFA deficiency within two weeks, and Intralipid which accounted for 4% of the total caloric intake (2% as linoleate) satisfied the EFA requirement.

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