[Abstract] [Full Text PDF] (in Japanese / 2604KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 83(7): 665-676, 1982


Original article

FOLLOW-UP STUDIES ON PANCREATECTOMY FOR CARCINOMA OF HEAD OF THE PANCREAS WITH RESPECT TO FACTORS INFLUENCING PROGNOSIS

The First Department of Surgery, Faculty of Medicine, Kyoto University, Kyoto, Japan (Director: Prof. T. Tobe)

Tadao Manabe, Takashi Suzuki, Kotara Uchida, Takayoshi Tobe

Forty-two patients underwent pancreatectomy for carcinoma of head of the pancreas were reviewed with respect to factors influencing prognosis.
One, two, three and five years survival rates in this series were 44.4%, 36.7%, 28.0% and 14.3% respectively. The size of the tumor influenced survival time with relation to the histology of the carcinoma. The capsular invasion of the tumor apparently correlated with length of survival : mean survival times were 43.8 months in S0, 28.6 months in S1, 8.6 months in S2 and 6.9 months in S3. In patients with invasion of carcinoma to pertinent arteries, portal system, retroperitoneal tissues or duodenum, survival time was shorter than those without invasion. Histopathologically, INF and v of the carcinoma evidently influenced the prognosis. The patients without detectable lymph node metastasis, n0, themean survival time was 57.0 months. In patients with lymph node metastasis of n1, n2 and n3, survival times were 16.7, 4.0 and 6.0 months respectively.
Survival rates are improving in patients with total pancreatectomy when compared to those with pancreaticoduodenectomy. En bloc pancreatectomy with portal vein resection would carry a better survival for patients with carcinoma of the pancreas.


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