J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 431KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 83(4): 338-344, 1982

Original article

SECRETORY COMPONENT IN SERA FROM PATIENTS WITH CARCINOMAS DETERMINED WITH A SENSITIVE ENZYME IMMUNOASSAY

*) The First Department of Surgery, Nagoya University School of Medicine
**) Department of Biochemistry, Institute for Developmental Research, Aichi Prefectural Colony

Yukio Ishiguro*), Takahiro Ito*), Masahiro Nagaya*), Kanefusa Kato**)

To know whether serum SC is a valuable marker substance for diagnosis of cancer patients, serum levels of secretory component (SC) were determined in patients with various carcinomas or nonneoplastic diseases, and in healthy control by means of a sensitive enzyme immunoassay system. The levels in healthy individuals (n=48) were 67.3±19.9ng/ml. Those in patients with non-neoplastic diseases were 114.3±46.4ng/ml and those in patients with carcinomas ranged widely from 47 to 560ng/ml (176.6±112.2ng/ml). These results indicate that the measurement of serum SC may provide a valuable diagnostic test for the routine screening and subsequent therapeutic monitoring of carcinomas.

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